Cas号：6217-54-5
别名：Docosahexaenoic acid；Cervonic Acid;DHA
an endogenous omega-3 fatty acid, acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR).
Docosahexaenoic Acid
化学数据
分子量 328.49
分子式C22H32O2
Cas号6217-54-5
Solubility (25°C) *
DMSO
100.0 mg/mL,Need ultrasonic
Ethanol
50.0 mg/mL (152.2 mM) warming
生物活性
产品描述
Docosahexaenoic acid, an endogenous omega-3 fatty acid, acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR).
产品应用
DHA是一种必需脂肪酸，其在神经组织中属最丰富的ω-3脂肪酸，特别是在视网膜和大脑。 DHA构成高达40％的视网膜和神经细胞膜的多不饱和脂肪酸总量池。使用鱼油DHA膳食补充剂，可抑制动脉粥样硬化和延误光感受器变性的视网膜色素变性的进度。新生儿的DHA不足会导致发育缺陷，大鼠DHA不足可能导致高血压。
用途及描述：科研试剂，广泛应用于分子生物学，药理学等科研方面，严禁用于人体。DHA是一种对人体非常重要的不饱和脂肪酸,DHA是神经系统细胞生长及维持的一种主要成分，是大脑和视网膜的重要构成成分，在人体大脑皮层中含量高达20%，在眼睛视网膜中所占比例约50%,对胎婴儿智力和视力发育至关重要。本品可用于相关领域的科研实验。
参考文献
[1] Oboh A, Kabeya N, et al. Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are
widespread among teleost fish. Sci Rep. 2017 Jun 20;7(1):3889.
[2] Oliver E, McGillicuddy FC, et al. Docosahexaenoic acid attenuates macrophage-induced inflammation and improves
insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. J Nutr Biochem. 2012 Sep;23(9):1192-200.
Cas号：6217-54-5，别名：Docosahexaenoic acid；Cervonic Acid;DHA，an endogenous omega-3 fatty acid, acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR).